Patient Education Tool

Antihypertensive Lisinopril patient education tool Lisinopril is mainly indicated for various types of hypertension in which it inhibits the formation of angiotensin II from angiotensin I, the potent vasoconstrictor that rises peripheral resistance hence hypertension. However, it also has other therapeutic indications such as; heart failure, prophylaxis of various cardiovascular events myocardial infarction in particular (Vishnevetsky, Walters & Tan, 2017). A number of factors affect its therapeutic efficacy; age and ethnic background, lisinopril just like any other angiotensin converting enzyme(ACE) inhibitors is more appropriate as an initial therapy to young Caucasians. Patients from the Afro-Caribbean origin and those over the age of 55 years do respond less with ACE inhibitors a class in which lisinopril belongs. When used in the geriatrics there is increased chances of postural hypotension, hence need to closely monitor the dose and the patient.

Caucasians have less chances of developing ACE inhibitor induced angiodema as compared to African-Americans or the Afro-carribeans. Use of this drug ought to be substituted with beta blockers or closely monitored in the said population. However, if used then antihistamines and epinephrine should be at hand to counter ACE inhibitor induced angiodema manifesting as respiratory obstruction and distress; considering the age, lisinopril is well tolerated among the elderly however orthostatic hypotension may occur, the patient has to be advised to take the drug at bed time and if not possible to always have rest after taking the drug, alternatively he/she may sit or lie down briefly upon feeling dizziness or lightheadness, this serves to promote the venous return to brain cells.