Alzheimers disease review

Document Type:Thesis

Subject Area:Education

Document 1

edu/wp-content/uploads/2014/12/Fall-2014-Alzheimers-Disease. pdf Alzheimer’s disease review Igor O. Korolev in his research paper, a clinical and basic science on Alzheimer's disease (AD) published on the 4th September 2014, concisely discusses on the potentially dangerous Alzheimer's disease. On the first section, Korolev expansively introduces the disease and elaborates on the plight of those affected. While focusing on the otherwise endless effects of the disease, he sheds light on its meaning, causes and its end results. Moreover, pseudo-dementia’ is potentially treatable and occurs secondary to other medical conditions – depression, nutrition deficiencies, endocrine disorder. On this article, signs and symptoms of Alzheimer's disease have also been pointed out. Although, over time, the disease greatly impairs the memory – especially the recent memories increase in forgetfulness and confusion may be the only initially observable symptoms.

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On the second section of the article, the author points out the key causative factors to Alzheimer's disease. According to scientists, in most people, the disease is caused by such factors as; heredity, lifestyle and environmental factors. Moreover, he stresses that the diseases has proven itself quite a jargon and hence has not been deeply understood. Furthermore, the therapy for the disease is still in its infancy. Probably, medications for the treatment of probable Alzheimer's diseases extenuate the symptoms but do not alter its continuation or reverse the cause of Alzheimer's disease itself. In fact, presently, the mainstay of Alzheimer’s disease therapy is drugs that only target neurotransmitter systems in the brain. Since the disease primarily destroys glutamate and cetylcholine-producing neurons and their associated synapses, this destruction correlates perfectly with early mental signs and symptoms of Alzheimer's disease.

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The paper is based on two key hypotheses on which it is written upon – the first hypothesis states that Alzheimer diseases causes dementia while the second states that Alzheimer disease usually affects the elderly. The author highly depends on surveys and random sampling as the main methods of data collection. Figuratively, he randomly samples and contacts surveys on both patients and doctors as well as clinical professionals on the topic (Alzheimer’s disease). Generally, 200 respondents are surveyed. Among them are 100 patients from different hospitals and 100 clinical professionals doctors included. Additionally, those affected may undergo personality changes and my later display personal characters far from what was originally their personality. It is this disease (AD) that commonly causes dementia leading to impairments that cause the loss of social skills.

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As a result of the disease, cells of the brain degenerate and die, eventually causing enormous decline in memory and mental functions. As a result, he predicts that, within a given population, the record for those suffering from dementia is thus expected to increase from 36 million currently to about 66 million by 2030. The research has various strengths in that it is very extensive. In reality, the paper is of great importance. Certainly because, with the tremendously growing population, many will find its findings very useful. Further, the notion of seemingly normal forgetfulness in life that many end up disregarding as a symptom for a potential dangerous ailment will undoubtedly find a worthwhile alternative. Thus, forgetfulness, just like any other type of human behavior may actually be a symptom to a dreadful disease.

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