Alzheimers Diseases Research

These individuals have lost interest in usual activities, the sleep for longer durations than usual, fond of misplacing items, frequent mood as well as personality changes, loss of memory, difficulty in performing duties, and problems with abstract thinking. This paper focuses on the progression of Alzheimer’s disease by critically evaluating the different stages of the disease and the treatment that depends entirely on the graded stages and the symptoms of the infection. Alzheimer’s Disease According to the finding s by Kelly (2008), Alzheimer’s Disease refers to a health condition in which an individual’s brain shrivels progressively and slowly after which it dies. Scientific assessment affirms that the nerve cells present in the skull stop functioning resulting in the malfunctioning of the essential brain signals.

Alzheimer’s gets considered as infection by the Geriatricians who study its pathogenesis, thus eliminating the analogy that Alzheimer’s is an age-related disorder. Families and friends or caregivers of an AD patient get affected as they become devastated when they see the person him/her change from the person they used to know to a stranger. Alzheimer’s Disease and the Brain The Central Nervous System (CNS) consist of the brain, the spinal cord as well as the nerves extending to all the body parts (Kelly, 2008). The cerebrum constitutes the “thinking region” of the brain and is involved in senses, problem-solving, memory, voluntary movements, and speech. Cerebrum comprise of the cerebral cortex in which thoughts become produced, memories become stored and senses of smell, sound, and sight get processed.

The Alzheimer’s Disease affects this section of the brain during its early progression. These tangled masses get referred to as Neurofibrillary Tangles (NFTS). Also, the presence of plaque or abnormal protein proteins gets logged between neurons, therefore, resulting in the death of cells in the brain in the chronic stage of Alzheimer’s Disease. “The rate with which the plaques and protein bites spreads varies from person to person and decreases the lifespan of a person to 8 or 20 years upon infection” (Kelly, 2008). Developmental Stages of Alzheimer’s Disease As per the publication by Iqbal et al. (2001), doctors usually consider mental disorders to have a visible symptom like depression and withdrawal from the world. At this point, determining what Alzheimer’s Disease is and the normal aging seems critical.

This stage becomes presented with difficulty in remembering and learning new information. Even though forgetting names, appointments or any data is familiar to healthy persons; frequent forgetting recently learned information gets associated with Alzheimer’s Disease. Moreover, patients with Alzheimer’s Disease have difficulty in managing finances, taking prescriptions on the set schedules as well as planning meals. For instance, an individual who has always appeared very careful about balancing checkbooks suddenly begins to overdraw accounts many times. Moderate Alzheimer’s Disease At this stage of infection, brain damage worsens and tends to spread to cover a more extensive section of the brain. Consequently, the infection affects the brain regions controlling sensory processing, thought, movement, reasoning as well as language. The symptoms become more apparent/pronounced.

The behavioral changes also become a real concern. The patient begins to forget old facts, have difficulty conducting duties, they quickly become agitated, have a problem in reasoning, reduced intellectual abilities, and indicate lack of concern for appearance. Studies reveal that warning light appearing in the evening stimulates a chemical reaction in the brain worsening symptoms of Alzheimer’s Disease, therefore making the disease exhausting. Moreover, hallucinations, delusions, and paranoia appear in persons with Alzheimer’s Disease. Personality changes dramatically. An individual becomes fearful, suspicious, confused (Kelly, 2008) or too dependent on a friend or a family member. Further, the persons with Alzheimer’s Disease lack concern for hygiene, appearance, and sleep becomes more noticeable as compared to a healthy person. The persons become passive.