Parkinsons disease case study
The disease is associated with several stages of development, that’ is, how it exists. Mostly it takes five stages; for the first stage, the signs and symptoms are more dominant to the extent that they are difficult to recognize as they don’t interfere with individual health; for the second stage, the signs become more intense, they worsen, weakening the individual such that he or she can’t do daily chores in comfortably; the third stage is also referred as the middle stage of the disease, the person moves slowly, might lose balance, and at some cases he or she might fall unexpectedly; eating, dressing, brushing and other common daily activities become difficult to practice; during the fourth stage, the individual becomes extra weak to the extent he or she can’t walk without support and the last stage is the major and final advanced stage of the disease, the person is totally unable to perform the normal daily activities (Pringsheim, et al.
This essay will discuss the Parkinson’s disease causes, the pattern of inheritance, treatment, diagnosis and its maintenance. Causes of Parkinson's Disease A substance called dopamine goes about as a messenger between two cerebrum regions - the substantia nigra and the corpus striatum - to deliver smooth, controlled developments. A large portion of the development related indications of Parkinson's infection is caused by an absence of dopamine because of the loss of dopamine-creating cells in the substantia nigra (Ng, et. By contemplating families with inherited Parkinson's ailment, researchers have recognized a few qualities that are related to the turmoil. Concentrate these qualities comprehend the reason for Parkinson's malady and may prompt new treatments (Posthuma, et al. Up until now, five qualities have been recognized that are conclusively connected with Parkinson's disease.
First is the SNCA that makes alpha-synuclein protein which in brain forms Lewy clumps (Ng, et al. The PARK 2, this gene makes the parkin protein that assists in breaking down proteins; PARK 7 gene that makes DJ-1 protein to for oxidative stress infection to the cells; PINK1 and lastly the LRRK 2 where mutations within this gene are linked to the Parkinson’s disease (Schlesinger, et al. Physical therapy might be whereby one will majorly focus on stretching exercise and balance (Posthuma, et al. Any problem related to speech, a speech-language pathologist will greatly help one improve. Medications Walking, tremor and movement problems might be managed through medication (Schlesinger, et al. Medications for most cases take the place of dopamine or increase it.
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